STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
glmUUDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (474 aa)    
Predicted Functional Partners:
glmM
Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
 
 
 0.982
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
 
  
 0.960
AEB83127.1
Manually curated; TIGRFAM: Nucleotide sugar dehydrogenase; KEGG: reu:Reut_B5375 UDP-glucose/GDP-mannose dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase, N-terminal; UDP-glucose/GDP-mannose dehydrogenase, dimerisation; UDP-glucose/GDP-mannose dehydrogenase, C-terminal; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
  
 
 0.939
glmS
Glucosamine--fructose-6-phosphate aminotransferase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
  
 0.928
AEB83699.1
PFAM: Polysaccharide biosynthesis protein CapD-like; KEGG: pol:Bpro_3983 polysaccharide biosynthesis protein CapD.
    
 0.925
AEB84029.1
TIGRFAM: UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal type; KEGG: dia:Dtpsy_2383 UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase.
 
  
 0.925
AEB83126.1
UDP-glucose 4-epimerase; KEGG: pol:Bpro_3996 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase.
  
 
 0.921
AEB87010.1
PFAM: Aminoglycoside phosphotransferase; KEGG: ajs:Ajs_4113 aminoglycoside phosphotransferase.
    
 0.917
AEB83104.1
TIGRFAM: Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; KEGG: rfr:Rfer_0711 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: Mannose-6-phosphate isomerase, type II, C-terminal; Nucleotidyl transferase; Belongs to the mannose-6-phosphate isomerase type 2 family.
    
 0.900
AEB83258.1
TIGRFAM: UDP-glucose 4-epimerase; KEGG: ajs:Ajs_0774 UDP-galactose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
   
 0.890
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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