Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
AEB83104.1TIGRFAM: Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; KEGG: rfr:Rfer_0711 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: Mannose-6-phosphate isomerase, type II, C-terminal; Nucleotidyl transferase; Belongs to the mannose-6-phosphate isomerase type 2 family. (480 aa)    
Predicted Functional Partners:
AEB85257.1
Phosphoglucomutase; KEGG: dia:Dtpsy_1830 phosphomannomutase; PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; Alpha-D-phosphohexomutase, alpha/beta/alpha domain III; Alpha-D-phosphohexomutase, C-terminal.
 
 0.985
pgi
KEGG: ajs:Ajs_0697 glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase (PGI); Belongs to the GPI family.
  
 
 0.959
AEB83025.1
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
  
 
 0.944
fbp
Fructose-bisphosphatase; KEGG: xtr:100486364 fructose-1,6-bisphosphatase class 1-like; PFAM: Fructose-1,6-bisphosphatase class 1/Sedoheputulose-1,7-bisphosphatase.
   
 0.938
glmS
Glucosamine--fructose-6-phosphate aminotransferase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
    
 0.934
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
    
 0.930
AEB83258.1
TIGRFAM: UDP-glucose 4-epimerase; KEGG: ajs:Ajs_0774 UDP-galactose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
  
 
 0.925
AEB82798.1
PFAM: Phosphotransferase system, fructose subfamily IIA component; KEGG: ajs:Ajs_0295 PTS system fructose subfamily IIA component.
    
 0.924
AEB84029.1
TIGRFAM: UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal type; KEGG: dia:Dtpsy_2383 UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase.
    
 0.916
AEB83496.1
TIGRFAM: Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Sugar transferase, PEP-CTERM system associated; KEGG: rfr:Rfer_0702 undecaprenyl-phosphate galactosephosphotransferase; PFAM: Bacterial sugar transferase.
 
  
 0.908
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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