Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEB83147.1KEGG: ajs:Ajs_0653 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase/ligase. (502 aa)    
Predicted Functional Partners:
AEB84319.1
KEGG: bxe:Bxe_C1205 putative superoxide dismutase; PFAM: Manganese/iron superoxide dismutase, C-terminal; SMART: Rhodanese-like.
  
 
 0.758
AEB83146.1
2OG-Fe(II) oxygenase; PFAM: Oxoglutarate/iron-dependent oxygenase; KEGG: dia:Dtpsy_0631 2OG-Fe(II) oxygenase.
     
 0.556
AEB83148.1
PFAM: Oxidoreductase FAD/NAD(P)-binding; Oxidoreductase, FAD-binding domain; KEGG: ctt:CtCNB1_2425 FAD-binding oxidoreductase.
     
 0.541
AEB83452.1
KEGG: dia:Dtpsy_2798 respiratory-chain NADH dehydrogenase domain 51 kDa subunit; PFAM: NADH:ubiquinone oxidoreductase, 51kDa subunit; NADH:ubiquinone oxidoreductase, 24kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; SMART: NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding.
    
 
 0.534
AEB83715.1
PFAM: Cytochrome P450; KEGG: ajs:Ajs_3226 cytochrome P450.
  
 0.482
rplF
Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
 0.480
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 
 0.451
AEB83133.1
KEGG: rfr:Rfer_0698 hypothetical protein.
  
 
 0.450
AEB86954.1
Acetate--CoA ligase; KEGG: gka:GK2759 acetyl-CoA synthetase (acetate-CoA ligase); PFAM: AMP-dependent synthetase/ligase.
 
0.425
rplC
50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
   
 
 0.411
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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