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Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEB83159.15'-nucleotidase; KEGG: vei:Veis_1630 5-nucleotidase; PFAM: 5-nucleotidase. (310 aa)    
Predicted Functional Partners:
AEB84812.1
KEGG: dia:Dtpsy_1679 protein of unknown function DUF152; TIGRFAM: Multi-copper polyphenol oxidoreductase, laccase; PFAM: Multi-copper polyphenol oxidoreductase, laccase; Belongs to the multicopper oxidase YfiH/RL5 family.
  
  
  0.913
amn
AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.
    
  0.903
cpdA
Metallophosphoesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.
    
  0.903
surE
Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
 0.901
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
     
 0.901
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
     
 0.901
AEB86212.1
KEGG: dia:Dtpsy_2894 phosphoribosyltransferase; PFAM: Phosphoribosyltransferase.
     
 0.901
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
     
 0.901
AEB83192.1
Cytidyltransferase-related domain protein; KEGG: ajs:Ajs_0701 cytidyltransferase-like protein; TIGRFAM: Cytidyltransferase-related; PFAM: NUDIX hydrolase domain; Cytidylyltransferase.
     
  0.900
AEB83219.1
Deoxyguanosinetriphosphate triphosphohydrolase-like protein; SMART: Metal-dependent phosphohydrolase, HD domain; TIGRFAM: Deoxyguanosinetriphosphate triphosphohydrolase; KEGG: ajs:Ajs_0736 deoxyguanosinetriphosphate triphosphohydrolase-like protein; HAMAP: Deoxyguanosinetriphosphate triphosphohydrolase, type 2; PFAM: Metal-dependent phosphohydrolase, HD subdomain; Belongs to the dGTPase family. Type 2 subfamily.
     
  0.900
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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