STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB83192.1Cytidyltransferase-related domain protein; KEGG: ajs:Ajs_0701 cytidyltransferase-like protein; TIGRFAM: Cytidyltransferase-related; PFAM: NUDIX hydrolase domain; Cytidylyltransferase. (342 aa)    
Predicted Functional Partners:
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
 
 
 0.965
cobB-2
NAD-dependent deacetylase; KEGG: dia:Dtpsy_1612 silent information regulator protein Sir2; HAMAP: NAD-dependent histone deacetylase, silent information regulator Sir2; PFAM: NAD-dependent histone deacetylase, silent information regulator Sir2; Belongs to the sirtuin family. Class III subfamily.
  
 
 0.961
pncB
Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.
 
  
 0.958
AEB83418.1
TIGRFAM: Nicotinate-nucleotide pyrophosphorylase; KEGG: dia:Dtpsy_2821 nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase, C-terminal domain; Quinolinate phosphoribosyl transferase, N-terminal; Belongs to the NadC/ModD family.
    
 0.940
AEB86728.1
KEGG: ajs:Ajs_0354 CinA domain-containing protein; TIGRFAM: CinA, C-terminal; PFAM: CinA, C-terminal; Belongs to the CinA family.
    
 0.934
nadK
Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
    
 0.930
AEB84027.1
PFAM: NUDIX hydrolase domain; KEGG: dia:Dtpsy_2385 NUDIX hydrolase.
 
  
 0.930
AEB86799.1
NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
    
  0.903
AEB86800.1
NAD(P) transhydrogenase, alpha subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family.
    
  0.903
surE
Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.902
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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