STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
msrQSulfoxide reductase heme-binding subunit yedZ; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalyti [...] (213 aa)    
Predicted Functional Partners:
msrP
Oxidoreductase molybdopterin binding protein; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to [...]
 
  
 0.992
AEB83098.1
PFAM: Oxidoreductase, molybdopterin-binding domain; KEGG: ctt:CtCNB1_4018 oxidoreductase, molybdopterin binding protein.
 
  
 0.925
AEB83759.1
TIGRFAM: Hydroxyisourate hydrolase; KEGG: dia:Dtpsy_1043 hydroxyisourate hydrolase; PFAM: Transthyretin/hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
  
  
 0.768
AEB83204.1
KEGG: ajs:Ajs_0712 cytochrome c assembly protein; TIGRFAM: Cytochrome c-type biogenesis protein CcsA; PFAM: Cytochrome c assembly protein.
       0.555
AEB83203.1
ResB family protein; PFAM: Cytochrome c biogenesis protein; KEGG: dia:Dtpsy_0691 ResB family protein.
       0.550
AEB84944.1
PFAM: Molybdopterin oxidoreductase; Molybdopterin oxidoreductase, Fe4S4 domain; Molydopterin dinucleotide-binding domain; BFD-like [2Fe-2S]-binding domain; KEGG: ajs:Ajs_2841 assimilatory nitrate reductase (NADH) alpha subunit apoprotein; SMART: Molybdopterin oxidoreductase, Fe4S4 domain; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
  
   
 0.427
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.