Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEB83403.1PFAM: UBA/THIF-type NAD/FAD binding fold; MoeZ/MoeB; KEGG: ajs:Ajs_3507 UBA/ThiF-type NAD/FAD binding protein. (254 aa)    
Predicted Functional Partners:
AEB83585.1
KEGG: dia:Dtpsy_2555 molybdopterin converting factor, subunit 1; TIGRFAM: Molybdopterin converting factor, subunit 1; PFAM: ThiamineS.
  
 0.986
iscS
Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
   
 0.967
AEB83590.1
PFAM: Molybdopterin biosynthesis MoaE; KEGG: ajs:Ajs_3199 molybdopterin synthase subunit MoaE.
 
 0.954
AEB85450.1
KEGG: dia:Dtpsy_1937 thiamine biosynthesis protein ThiS; TIGRFAM: ThiS, thiamine-biosynthesis; PFAM: ThiamineS.
  
 
 0.931
thiG
Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
  
 0.930
AEB83404.1
Carboxyl-terminal protease; TIGRFAM: Peptidase S41A, C-terminal peptidase; PFAM: Peptidase S41; PDZ/DHR/GLGF; KEGG: ajs:Ajs_3506 C-terminal processing peptidase-3; SMART: Peptidase S41; PDZ/DHR/GLGF; Belongs to the peptidase S41A family.
  
    0.807
thiC
Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
 
  
 0.806
AEB85576.1
Rhodanese-like protein; KEGG: dia:Dtpsy_1836 rhodanese domain protein; PFAM: Rhodanese-like; SMART: Rhodanese-like.
    
 0.742
AEB85452.1
KEGG: dia:Dtpsy_1939 thiamine-phosphate pyrophosphorylase; PFAM: Thiamine monophosphate synthase.
 
  
 0.741
moaC
Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
 
   
 0.738
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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