Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEB83423.1KEGG: reh:H16_A1911 AraC family transcriptional regulator; PFAM: HTH transcriptional regulator, AraC; SMART: Helix-turn-helix, AraC type, DNA binding domain. (289 aa)    
Predicted Functional Partners:
AEB83424.1
Uncharacterized peroxidase-related enzyme; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.
 
    0.755
AEB83421.1
PFAM: 5-carboxymethyl-2-hydroxymuconate isomerase; KEGG: dia:Dtpsy_2818 5-carboxymethyl-2-hydroxymuconate isomerase.
 
   
 0.551
AEB83422.1
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
       0.539
AEB84832.1
Regulatory protein TetR; PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; KEGG: pde:Pden_4681 TetR family transcriptional regulator.
  
   
 0.532
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.498
AEB82502.1
AraC protein arabinose-binding/dimerization; KEGG: dia:Dtpsy_0054 transcriptional regulator, AraC family; PFAM: HTH transcriptional regulator, AraC, arabinose-binding/dimerisation; SMART: Helix-turn-helix, AraC type, DNA binding domain.
 
 
 0.482
AEB82685.1
PFAM: Activator of Hsp90 ATPase homologue 1-like; KEGG: oca:OCAR_5014 activator of HSP90 ATPase 1 family protein.
 
     0.459
AEB85263.1
DNA repair protein and transcriptional regulator, AraC family; KEGG: ajs:Ajs_2020 DNA-O6-methylguanine--protein-cysteine S-methyltransferase.
 
   
 0.403
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
Server load: low (20%) [HD]