Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
selDSelenide, water dikinase; Synthesizes selenophosphate from selenide and ATP. (353 aa)    
Predicted Functional Partners:
AEB83440.1
KEGG: dia:Dtpsy_2803 tRNA 2-selenouridine synthase; TIGRFAM: tRNA 2-selenouridine synthase; SMART: Rhodanese-like; Belongs to the SelU family.
 
   
 0.942
AEB84955.1
Cysteine desulfurase, SufS subfamily; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
    
 0.924
AEB85445.1
Ferredoxin--NADP(+) reductase; KEGG: dia:Dtpsy_1933 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
     
 0.910
AEB86036.1
Thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; manually curated; KEGG: dia:Dtpsy_2721 thioredoxin reductase; TIGRFAM: Thioredoxin reductase.
     
 0.910
iscS
Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
  
 
 0.902
AEB83442.1
PFAM: C4-dicarboxylate transporter/malic acid transport protein; KEGG: dia:Dtpsy_2801 C4-dicarboxylate transporter/malic acid transport protein.
       0.785
AEB83443.1
ATPase-like, ParA/MinD; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
     
 0.653
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
     
 0.555
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 
 0.512
fdhD
Formate dehydrogenase subunit FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.
     
 0.496
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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