Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEB83480.1KEGG: ajs:Ajs_3447 hypothetical protein; PFAM: Domain of unknown function DUF21; Cystathionine beta-synthase, core; Transporter-associated domain; SMART: Cystathionine beta-synthase, core. (442 aa)    
Predicted Functional Partners:
AEB86959.1
PFAM: Peptidase M4, propeptide, PepSY; KEGG: dia:Dtpsy_3432 propeptide PepSY amd peptidase M4.
   
    0.496
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.490
AEB84604.1
PFAM: Amine oxidase; KEGG: xal:XALc_2703 protoporphyrinogen oxidase protein.
  
     0.474
AEB83477.1
KEGG: ajs:Ajs_3450 DNA repair protein RadC; TIGRFAM: Uncharacterised protein family UPF0758; PFAM: Uncharacterised protein family UPF0758; Belongs to the UPF0758 family.
 
    0.460
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
       0.458
ybeY
Metalloprotease ybeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
  
  
 0.448
AEB83478.1
PFAM: Peptidyl-prolyl cis-trans isomerase, FKBP-type; KEGG: dia:Dtpsy_2776 peptidylprolyl isomerase FKBP-type.
  
    0.440
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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