Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
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textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEB83499.1KEGG: ctt:CtCNB1_0831 two component transcriptional regulator, winged; PFAM: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal. (243 aa)    
Predicted Functional Partners:
AEB83497.1
Multi-sensor signal transduction histidine kinase; KEGG: dac:Daci_5418 histidine kinase; PFAM: CHASE2; ATPase-like, ATP-binding domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS.
 
 
 0.925
AEB84157.1
TIGRFAM: Signal transduction histidine kinase, heavy metal sensor; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; KEGG: gbm:Gbem_2673 HAMP domain-containing sensor histidine kinase; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain.
 
 
 0.856
AEB84848.1
Integral membrane sensor signal transduction histidine kinase; KEGG: pol:Bpro_1451 histidine kinase; PFAM: Two-component sensor kinase N-terminal; ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain.
 
 
 0.827
AEB86397.1
TIGRFAM: PAS; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold-4; KEGG: dac:Daci_0735 PAS/PAC sensor signal transduction histidine kinase; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS.
 
 
 0.822
AEB83376.1
Manually curated; PFAM: Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; ATPase-like, ATP-binding domain; KEGG: dac:Daci_2713 histidine kinase; SMART: Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; ATPase-like, ATP-binding domain.
 
 
 0.814
AEB86401.1
TIGRFAM: PAS; PFAM: ATPase-like, ATP-binding domain; PAS fold-4; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; KEGG: dac:Daci_0735 PAS/PAC sensor signal transduction histidine kinase; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS.
 
 
 0.797
AEB82690.1
KEGG: dia:Dtpsy_0212 histidine kinase; PFAM: ATPase-like, ATP-binding domain; HAMP linker domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; HAMP linker domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain.
 
 
 0.795
AEB85736.1
Heavy metal sensor signal transduction histidine kinase; Member of a two-component regulatory system.
 
 
 0.794
AEB84872.1
KEGG: dia:Dtpsy_1753 histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain.
 
 
 0.779
AEB86221.1
KEGG: aav:Aave_3963 integral membrane sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain.
 
 
 0.762
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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