Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEB83630.1Alpha-2-macroglobulin domain protein; PFAM: Alpha-2-macroglobulin, N-terminal; Alpha-2-macroglobulin, N-terminal 2; Alpha-2-macroglobulin; KEGG: dia:Dtpsy_2661 alpha-2-macroglobulin domain protein. (1978 aa)    
Predicted Functional Partners:
AEB83640.1
TIGRFAM: Penicillin-binding protein 1C; KEGG: ajs:Ajs_3299 penicillin-binding protein 1C; PFAM: Glycosyl transferase, family 51; Penicillin-binding protein, transpeptidase; Penicillin-binding, C-terminal.
 
   
 0.880
AEB83631.1
Metallophosphoesterase; PFAM: Metallo-dependent phosphatase; KEGG: dac:Daci_4972 metallophosphoesterase.
       0.658
AEB85170.1
Trypsin; PFAM: Peptidase S1/S6, chymotrypsin/Hap; KEGG: mmu:16621 kallikrein B, plasma 1; SMART: Peptidase S1/S6, chymotrypsin/Hap.
    
 0.594
AEB83629.1
KEGG: ajs:Ajs_3311 hypothetical protein.
       0.507
nrdR
Ribonucleotide reductase regulator NrdR-like protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
   
   0.496
argH
TIGRFAM: Argininosuccinate lyase; KEGG: dia:Dtpsy_2664 argininosuccinate lyase; PFAM: Lyase 1, N-terminal.
  
    0.479
AEB84174.1
PFAM: Abortive phage infection; KEGG: pph:Ppha_0341 hypothetical protein.
  
 
 
 0.439
AEB84804.1
ZipA FtsZ-binding region protein; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. Belongs to the ZipA family.
  
     0.417
AEB84502.1
PFAM: Protein of unknown function DUF748; Outer membrane protein, OmpA/MotB, C-terminal; KEGG: ajs:Ajs_1662 hypothetical protein.
 
     0.407
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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