Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEB83653.1Procollagen-proline dioxygenase; PFAM: Oxoglutarate/iron-dependent oxygenase; KEGG: ajs:Ajs_3293 2OG-Fe(II) oxygenase; SMART: Prolyl 4-hydroxylase, alpha subunit. (284 aa)    
Predicted Functional Partners:
AEB83069.1
KEGG: dia:Dtpsy_0592 ornithine cyclodeaminase; PFAM: Ornithine cyclodeaminase/mu-crystallin.
     
  0.900
AEB85459.1
Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
     
  0.900
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
     
  0.900
AEB83654.1
Protein of unknown function DUF328; PFAM: Uncharacterised protein family UPF0246; KEGG: dia:Dtpsy_2644 hypothetical protein; Belongs to the UPF0246 family.
       0.842
queF
7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
       0.728
rne
Ribonuclease, Rne/Rng family; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily.
       0.497
AEB82896.1
KEGG: cph:Cpha266_1840 TPR repeat-containing protein; PFAM: Tetratricopeptide TPR-1; Tetratricopeptide TPR2; SMART: Tetratricopeptide repeat.
 
     0.480
AEB83785.1
KEGG: xtr:100495621 UPF0065 protein in clcB-clcD intergenic region-like.
  
     0.413
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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