Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEB83722.1Tryptophanase; KEGG: rfr:Rfer_2475 tryptophanase; PFAM: Aromatic amino acid beta-eliminating lyase/threonine aldolase. (456 aa)    
Predicted Functional Partners:
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
    
 0.924
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
    
 0.922
trpB-2
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
     
 0.913
AEB83720.1
PFAM: Peptidase U32; KEGG: ajs:Ajs_3221 peptidase U32.
       0.495
AEB83721.1
PFAM: Peptidase U32; KEGG: ajs:Ajs_3220 peptidase U32.
       0.495
ubiX
3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.
     
 0.488
AEB83718.1
DGC domain protein; PFAM: DGC; KEGG: ajs:Ajs_3223 hypothetical protein.
       0.466
AEB83719.1
PFAM: SCP2 sterol-binding domain; KEGG: ajs:Ajs_3222 hypothetical protein.
       0.466
AEB82491.1
Protein of unknown function UPF0153; PFAM: Uncharacterised protein family UPF0153; KEGG: dia:Dtpsy_0043 protein of unknown function UPF0153.
    
   0.440
AEB84354.1
Chorismate mutase; TIGRFAM: Gamma/beta/epsilon proteobacterial P-protein, chorismate mutase domain; PFAM: Prephenate dehydratase; Chorismate mutase, type II; Amino acid-binding ACT; KEGG: dia:Dtpsy_1394 chorismate mutase; SMART: Chorismate mutase.
      
 0.404
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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