Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
apaHBis(5'-nucleosyl)-tetraphosphatase (symmetrical); Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. (281 aa)    
Predicted Functional Partners:
AEB84377.1
KEGG: nde:NIDE0081 hypothetical protein.
   
 0.884
AEB84570.1
KEGG: maq:Maqu_0130 hypothetical protein.
   
 0.846
AEB85533.1
PFAM: Ankyrin repeat; KEGG: dia:Dtpsy_1983 ankyrin.
   
 0.846
apaG
Protein ApaG; KEGG: dia:Dtpsy_0349 ApaG; HAMAP: Uncharacterised protein family ApaG; PFAM: ApaG domain.
  
  
 0.804
AEB84742.1
KEGG: dia:Dtpsy_1738 peptidylprolyl isomerase; PFAM: Peptidyl-prolyl cis-trans isomerase, FKBP-type.
    
 0.789
AEB85934.1
KEGG: dia:Dtpsy_2493 peptidylprolyl isomerase; PFAM: Peptidyl-prolyl cis-trans isomerase, FKBP-type.
    
 0.789
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
   
 
 0.766
groL
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.755
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
 
 0.744
AEB83276.1
PFAM: Stringent starvation protein B; KEGG: dia:Dtpsy_0756 stringent starvation protein B.
  
     0.722
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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