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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
derRibosome-associated GTPase EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. (447 aa)    
Predicted Functional Partners:
gpsA
Manually curated; HAMAP: Glycerol-3-phosphate dehydrogenase, NAD-dependent; KEGG: xtr:100490244 glycerol-3-phosphate dehydrogenase [NAD(P)+]-like; PFAM: Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal; Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
  
 0.941
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
 
  
 0.914
cmk
Cytidylate kinase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate; Belongs to the cytidylate kinase family. Type 1 subfamily.
  
 0.894
AEB83806.1
TIGRFAM: Pseudouridine synthase, RsuA/RluB/E/F; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; RNA-binding S4; KEGG: dia:Dtpsy_1085 pseudouridine synthase; SMART: RNA-binding S4; Belongs to the pseudouridine synthase RsuA family.
 
  
 0.860
bamB
Outer membrane assembly lipoprotein YfgL; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
  
 0.857
secA
Protein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family.
 
  
 0.848
AEB83813.1
PFAM: Protein of unknown function DUF2133; KEGG: dia:Dtpsy_1092 hypothetical protein.
  
  
 0.842
AEB84514.1
KEGG: ajs:Ajs_2558 GTP-binding protein TypA; TIGRFAM: GTP-binding protein TypA; Small GTP-binding protein; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFG/EF2, C-terminal.
 
  
 0.839
AEB83824.1
Pseudouridine synthase Rsu; KEGG: ajs:Ajs_1183 ribosomal small subunit pseudouridine synthase A; TIGRFAM: Pseudouridine synthase, RsuA/RluB/E/F; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; Belongs to the pseudouridine synthase RsuA family.
 
  
 0.814
hisS
PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved domain; Anticodon-binding; TIGRFAM: Histidyl-tRNA synthetase, class IIa, subgroup; HAMAP: Histidyl-tRNA synthetase, class IIa, subgroup; KEGG: dia:Dtpsy_1091 histidyl-tRNA synthetase.
 
  
 0.808
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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