| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEB82821.1 | AEB83848.1 | Alide2_0397 | Alide2_1449 | PFAM: Cytochrome c, class I; KEGG: aav:Aave_0385 cytochrome c, class I. | PFAM: Protein of unknown function DUF2069, membrane; KEGG: dia:Dtpsy_1118 membrane protein-like protein. | 0.633 |
| AEB82821.1 | AEB86343.1 | Alide2_0397 | Alide2_4024 | PFAM: Cytochrome c, class I; KEGG: aav:Aave_0385 cytochrome c, class I. | PFAM: Uncharacterised conserved protein UCP019883, membrane; KEGG: dia:Dtpsy_0886 putative transmembrane protein. | 0.644 |
| AEB83616.1 | AEB83848.1 | Alide2_1212 | Alide2_1449 | SlyX family protein; PFAM: SlyX; KEGG: dia:Dtpsy_2515 SlyX family protein. | PFAM: Protein of unknown function DUF2069, membrane; KEGG: dia:Dtpsy_1118 membrane protein-like protein. | 0.647 |
| AEB83616.1 | AEB84778.1 | Alide2_1212 | Alide2_2414 | SlyX family protein; PFAM: SlyX; KEGG: dia:Dtpsy_2515 SlyX family protein. | TIGRFAM: PAS; PFAM: ATPase-like, ATP-binding domain; PAS fold; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; KEGG: dia:Dtpsy_1656 PAS/PAC sensor signal transduction histidine kinase; SMART: ATPase-like, ATP-binding domain; PAS; PAC motif; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain. | 0.497 |
| AEB83845.1 | AEB83847.1 | Alide2_1446 | Alide2_1448 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | D-lactate dehydrogenase (cytochrome); KEGG: dia:Dtpsy_1117 FAD linked oxidase domain protein; PFAM: FAD-linked oxidase, C-terminal; FAD linked oxidase, N-terminal. | 0.636 |
| AEB83845.1 | AEB83848.1 | Alide2_1446 | Alide2_1449 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | PFAM: Protein of unknown function DUF2069, membrane; KEGG: dia:Dtpsy_1118 membrane protein-like protein. | 0.647 |
| AEB83845.1 | AEB83849.1 | Alide2_1446 | Alide2_1450 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Ribonuclease BN; KEGG: dia:Dtpsy_1119 ribonuclease BN; TIGRFAM: Ribonuclease BN; PFAM: Ribonuclease BN-related. | 0.478 |
| AEB83845.1 | thyA | Alide2_1446 | Alide2_1447 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.999 |
| AEB83847.1 | AEB83845.1 | Alide2_1448 | Alide2_1446 | D-lactate dehydrogenase (cytochrome); KEGG: dia:Dtpsy_1117 FAD linked oxidase domain protein; PFAM: FAD-linked oxidase, C-terminal; FAD linked oxidase, N-terminal. | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.636 |
| AEB83847.1 | AEB83848.1 | Alide2_1448 | Alide2_1449 | D-lactate dehydrogenase (cytochrome); KEGG: dia:Dtpsy_1117 FAD linked oxidase domain protein; PFAM: FAD-linked oxidase, C-terminal; FAD linked oxidase, N-terminal. | PFAM: Protein of unknown function DUF2069, membrane; KEGG: dia:Dtpsy_1118 membrane protein-like protein. | 0.837 |
| AEB83847.1 | AEB83849.1 | Alide2_1448 | Alide2_1450 | D-lactate dehydrogenase (cytochrome); KEGG: dia:Dtpsy_1117 FAD linked oxidase domain protein; PFAM: FAD-linked oxidase, C-terminal; FAD linked oxidase, N-terminal. | Ribonuclease BN; KEGG: dia:Dtpsy_1119 ribonuclease BN; TIGRFAM: Ribonuclease BN; PFAM: Ribonuclease BN-related. | 0.611 |
| AEB83847.1 | thyA | Alide2_1448 | Alide2_1447 | D-lactate dehydrogenase (cytochrome); KEGG: dia:Dtpsy_1117 FAD linked oxidase domain protein; PFAM: FAD-linked oxidase, C-terminal; FAD linked oxidase, N-terminal. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.634 |
| AEB83848.1 | AEB82821.1 | Alide2_1449 | Alide2_0397 | PFAM: Protein of unknown function DUF2069, membrane; KEGG: dia:Dtpsy_1118 membrane protein-like protein. | PFAM: Cytochrome c, class I; KEGG: aav:Aave_0385 cytochrome c, class I. | 0.633 |
| AEB83848.1 | AEB83616.1 | Alide2_1449 | Alide2_1212 | PFAM: Protein of unknown function DUF2069, membrane; KEGG: dia:Dtpsy_1118 membrane protein-like protein. | SlyX family protein; PFAM: SlyX; KEGG: dia:Dtpsy_2515 SlyX family protein. | 0.647 |
| AEB83848.1 | AEB83845.1 | Alide2_1449 | Alide2_1446 | PFAM: Protein of unknown function DUF2069, membrane; KEGG: dia:Dtpsy_1118 membrane protein-like protein. | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.647 |
| AEB83848.1 | AEB83847.1 | Alide2_1449 | Alide2_1448 | PFAM: Protein of unknown function DUF2069, membrane; KEGG: dia:Dtpsy_1118 membrane protein-like protein. | D-lactate dehydrogenase (cytochrome); KEGG: dia:Dtpsy_1117 FAD linked oxidase domain protein; PFAM: FAD-linked oxidase, C-terminal; FAD linked oxidase, N-terminal. | 0.837 |
| AEB83848.1 | AEB83849.1 | Alide2_1449 | Alide2_1450 | PFAM: Protein of unknown function DUF2069, membrane; KEGG: dia:Dtpsy_1118 membrane protein-like protein. | Ribonuclease BN; KEGG: dia:Dtpsy_1119 ribonuclease BN; TIGRFAM: Ribonuclease BN; PFAM: Ribonuclease BN-related. | 0.668 |
| AEB83848.1 | AEB84778.1 | Alide2_1449 | Alide2_2414 | PFAM: Protein of unknown function DUF2069, membrane; KEGG: dia:Dtpsy_1118 membrane protein-like protein. | TIGRFAM: PAS; PFAM: ATPase-like, ATP-binding domain; PAS fold; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; KEGG: dia:Dtpsy_1656 PAS/PAC sensor signal transduction histidine kinase; SMART: ATPase-like, ATP-binding domain; PAS; PAC motif; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain. | 0.662 |
| AEB83848.1 | AEB85617.1 | Alide2_1449 | Alide2_3276 | PFAM: Protein of unknown function DUF2069, membrane; KEGG: dia:Dtpsy_1118 membrane protein-like protein. | KEGG: dia:Dtpsy_1366 phasin family protein; TIGRFAM: Phasin, subfamily 1; PFAM: Phasin. | 0.697 |
| AEB83848.1 | AEB86343.1 | Alide2_1449 | Alide2_4024 | PFAM: Protein of unknown function DUF2069, membrane; KEGG: dia:Dtpsy_1118 membrane protein-like protein. | PFAM: Uncharacterised conserved protein UCP019883, membrane; KEGG: dia:Dtpsy_0886 putative transmembrane protein. | 0.656 |