| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEB83275.1 | AEB83849.1 | Alide2_0862 | Alide2_1450 | PFAM: Glutathione S-transferase, N-terminal; Glutathione S-transferase, C-terminal; KEGG: dia:Dtpsy_0755 glutathione S-transferase domain protein. | Ribonuclease BN; KEGG: dia:Dtpsy_1119 ribonuclease BN; TIGRFAM: Ribonuclease BN; PFAM: Ribonuclease BN-related. | 0.401 |
| AEB83845.1 | AEB83847.1 | Alide2_1446 | Alide2_1448 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | D-lactate dehydrogenase (cytochrome); KEGG: dia:Dtpsy_1117 FAD linked oxidase domain protein; PFAM: FAD-linked oxidase, C-terminal; FAD linked oxidase, N-terminal. | 0.626 |
| AEB83845.1 | AEB83848.1 | Alide2_1446 | Alide2_1449 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | PFAM: Protein of unknown function DUF2069, membrane; KEGG: dia:Dtpsy_1118 membrane protein-like protein. | 0.647 |
| AEB83845.1 | AEB83849.1 | Alide2_1446 | Alide2_1450 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Ribonuclease BN; KEGG: dia:Dtpsy_1119 ribonuclease BN; TIGRFAM: Ribonuclease BN; PFAM: Ribonuclease BN-related. | 0.476 |
| AEB83845.1 | thyA | Alide2_1446 | Alide2_1447 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.999 |
| AEB83847.1 | AEB83845.1 | Alide2_1448 | Alide2_1446 | D-lactate dehydrogenase (cytochrome); KEGG: dia:Dtpsy_1117 FAD linked oxidase domain protein; PFAM: FAD-linked oxidase, C-terminal; FAD linked oxidase, N-terminal. | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.626 |
| AEB83847.1 | AEB83848.1 | Alide2_1448 | Alide2_1449 | D-lactate dehydrogenase (cytochrome); KEGG: dia:Dtpsy_1117 FAD linked oxidase domain protein; PFAM: FAD-linked oxidase, C-terminal; FAD linked oxidase, N-terminal. | PFAM: Protein of unknown function DUF2069, membrane; KEGG: dia:Dtpsy_1118 membrane protein-like protein. | 0.842 |
| AEB83847.1 | AEB83849.1 | Alide2_1448 | Alide2_1450 | D-lactate dehydrogenase (cytochrome); KEGG: dia:Dtpsy_1117 FAD linked oxidase domain protein; PFAM: FAD-linked oxidase, C-terminal; FAD linked oxidase, N-terminal. | Ribonuclease BN; KEGG: dia:Dtpsy_1119 ribonuclease BN; TIGRFAM: Ribonuclease BN; PFAM: Ribonuclease BN-related. | 0.640 |
| AEB83847.1 | thyA | Alide2_1448 | Alide2_1447 | D-lactate dehydrogenase (cytochrome); KEGG: dia:Dtpsy_1117 FAD linked oxidase domain protein; PFAM: FAD-linked oxidase, C-terminal; FAD linked oxidase, N-terminal. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.644 |
| AEB83848.1 | AEB83845.1 | Alide2_1449 | Alide2_1446 | PFAM: Protein of unknown function DUF2069, membrane; KEGG: dia:Dtpsy_1118 membrane protein-like protein. | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.647 |
| AEB83848.1 | AEB83847.1 | Alide2_1449 | Alide2_1448 | PFAM: Protein of unknown function DUF2069, membrane; KEGG: dia:Dtpsy_1118 membrane protein-like protein. | D-lactate dehydrogenase (cytochrome); KEGG: dia:Dtpsy_1117 FAD linked oxidase domain protein; PFAM: FAD-linked oxidase, C-terminal; FAD linked oxidase, N-terminal. | 0.842 |
| AEB83848.1 | AEB83849.1 | Alide2_1449 | Alide2_1450 | PFAM: Protein of unknown function DUF2069, membrane; KEGG: dia:Dtpsy_1118 membrane protein-like protein. | Ribonuclease BN; KEGG: dia:Dtpsy_1119 ribonuclease BN; TIGRFAM: Ribonuclease BN; PFAM: Ribonuclease BN-related. | 0.688 |
| AEB83848.1 | thyA | Alide2_1449 | Alide2_1447 | PFAM: Protein of unknown function DUF2069, membrane; KEGG: dia:Dtpsy_1118 membrane protein-like protein. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.646 |
| AEB83849.1 | AEB83275.1 | Alide2_1450 | Alide2_0862 | Ribonuclease BN; KEGG: dia:Dtpsy_1119 ribonuclease BN; TIGRFAM: Ribonuclease BN; PFAM: Ribonuclease BN-related. | PFAM: Glutathione S-transferase, N-terminal; Glutathione S-transferase, C-terminal; KEGG: dia:Dtpsy_0755 glutathione S-transferase domain protein. | 0.401 |
| AEB83849.1 | AEB83845.1 | Alide2_1450 | Alide2_1446 | Ribonuclease BN; KEGG: dia:Dtpsy_1119 ribonuclease BN; TIGRFAM: Ribonuclease BN; PFAM: Ribonuclease BN-related. | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.476 |
| AEB83849.1 | AEB83847.1 | Alide2_1450 | Alide2_1448 | Ribonuclease BN; KEGG: dia:Dtpsy_1119 ribonuclease BN; TIGRFAM: Ribonuclease BN; PFAM: Ribonuclease BN-related. | D-lactate dehydrogenase (cytochrome); KEGG: dia:Dtpsy_1117 FAD linked oxidase domain protein; PFAM: FAD-linked oxidase, C-terminal; FAD linked oxidase, N-terminal. | 0.640 |
| AEB83849.1 | AEB83848.1 | Alide2_1450 | Alide2_1449 | Ribonuclease BN; KEGG: dia:Dtpsy_1119 ribonuclease BN; TIGRFAM: Ribonuclease BN; PFAM: Ribonuclease BN-related. | PFAM: Protein of unknown function DUF2069, membrane; KEGG: dia:Dtpsy_1118 membrane protein-like protein. | 0.688 |
| AEB83849.1 | AEB86114.1 | Alide2_1450 | Alide2_3789 | Ribonuclease BN; KEGG: dia:Dtpsy_1119 ribonuclease BN; TIGRFAM: Ribonuclease BN; PFAM: Ribonuclease BN-related. | PFAM: Peptidyl-prolyl cis-trans isomerase, FKBP-type; KEGG: dia:Dtpsy_0919 fkbp-type peptidyl-prolyl cis-trans isomerase. | 0.417 |
| AEB83849.1 | thyA | Alide2_1450 | Alide2_1447 | Ribonuclease BN; KEGG: dia:Dtpsy_1119 ribonuclease BN; TIGRFAM: Ribonuclease BN; PFAM: Ribonuclease BN-related. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.487 |
| AEB86114.1 | AEB83849.1 | Alide2_3789 | Alide2_1450 | PFAM: Peptidyl-prolyl cis-trans isomerase, FKBP-type; KEGG: dia:Dtpsy_0919 fkbp-type peptidyl-prolyl cis-trans isomerase. | Ribonuclease BN; KEGG: dia:Dtpsy_1119 ribonuclease BN; TIGRFAM: Ribonuclease BN; PFAM: Ribonuclease BN-related. | 0.417 |