STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB83849.1Ribonuclease BN; KEGG: dia:Dtpsy_1119 ribonuclease BN; TIGRFAM: Ribonuclease BN; PFAM: Ribonuclease BN-related. (417 aa)    
Predicted Functional Partners:
AEB83848.1
PFAM: Protein of unknown function DUF2069, membrane; KEGG: dia:Dtpsy_1118 membrane protein-like protein.
  
    0.668
AEB83847.1
D-lactate dehydrogenase (cytochrome); KEGG: dia:Dtpsy_1117 FAD linked oxidase domain protein; PFAM: FAD-linked oxidase, C-terminal; FAD linked oxidase, N-terminal.
       0.611
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
     
 0.485
AEB83845.1
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
       0.478
AEB86114.1
PFAM: Peptidyl-prolyl cis-trans isomerase, FKBP-type; KEGG: dia:Dtpsy_0919 fkbp-type peptidyl-prolyl cis-trans isomerase.
 
     0.418
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.406
AEB85747.1
ArsC family protein; KEGG: dia:Dtpsy_2230 arsenate reductase and related; TIGRFAM: Transcriptional regulator Spx/MgsR; PFAM: Arsenate reductase-like; Belongs to the ArsC family.
  
  
 0.403
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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