Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
AEB84441.1KEGG: tin:Tint_2912 DNA-directed DNA polymerase; PFAM: DNA-repair protein, UmuC-like. (428 aa)    
Predicted Functional Partners:
AEB84440.1
PFAM: Peptidase S24/S26A/S26B, conserved region; KEGG: tin:Tint_2913 peptidase S24/S26A/S26B, conserved region; Belongs to the peptidase S24 family.
 
 
 0.982
AEB82442.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.874
AEB85415.1
KEGG: vap:Vapar_6015 DNA polymerase II; PFAM: DNA-directed DNA polymerase, family B, conserved region; DNA-directed DNA polymerase, family B, exonuclease domain; SMART: DNA-directed DNA polymerase, family B.
   
 0.874
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.873
lexA
SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
 
 
 0.747
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.745
AEB85263.1
DNA repair protein and transcriptional regulator, AraC family; KEGG: ajs:Ajs_2020 DNA-O6-methylguanine--protein-cysteine S-methyltransferase.
  
 
 0.710
AEB84439.1
PFAM: Protein of unknown function DUF159; KEGG: tin:Tint_2914 protein of unknown function DUF159; Belongs to the SOS response-associated peptidase family.
 
   
 0.696
AEB85365.1
DNA polymerase III, alpha subunit; SMART: Polymerase/histidinol phosphatase, N-terminal; TIGRFAM: DNA polymerase III, alpha subunit; KEGG: dia:Dtpsy_1898 DNA polymerase III, alpha subunit; PFAM: Bacterial DNA polymerase III, alpha subunit; PHP, C-terminal; Nucleic acid binding, OB-fold, tRNA/helicase-type.
  
  
 0.646
AEB82872.1
Hypothetical protein; Manually curated; KEGG: aav:Aave_0642 hypothetical protein.
  
 
 0.610
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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