Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEB84474.1TIGRFAM: 2-methylisocitrate dehydratase AcnD, Fe/S-dependent; KEGG: dia:Dtpsy_2080 aconitate hydratase; PFAM: Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha; Aconitase A/isopropylmalate dehydratase small subunit, swivel. (867 aa)    
Predicted Functional Partners:
AEB84475.1
TIGRFAM: 2-methylcitrate synthase/citrate synthase type I; KEGG: ajs:Ajs_1635 methylcitrate synthase; PFAM: Citrate synthase-like; Belongs to the citrate synthase family.
 
 0.998
AEB84473.1
KEGG: dac:Daci_3586 AcnD-accessory protein PrpF; TIGRFAM: PrpF, AcnD-accessory; PFAM: PrpF protein.
 
 
 0.994
AEB85554.1
PFAM: Citrate synthase-like; KEGG: rme:Rmet_4144 citrate synthase.
 
 0.892
AEB85284.1
TIGRFAM: Isocitrate dehydrogenase NADP-dependent, prokaryotic; KEGG: aav:Aave_2572 isocitrate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase.
 
 0.890
fumC
Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.858
AEB84578.1
KEGG: dia:Dtpsy_2288 type II citrate synthase; TIGRFAM: Citrate synthase, type II; PFAM: Citrate synthase-like; Belongs to the citrate synthase family.
 
 0.853
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.845
AEB84472.1
Methylisocitrate lyase; KEGG: dac:Daci_3579 PEP phosphonomutase; PFAM: Isocitrate lyase/phosphorylmutase.
 
 0.840
AEB85373.1
2-oxoglutarate dehydrogenase, E1 subunit; SMART: Transketolase-like, pyrimidine-binding domain; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 component; KEGG: ajs:Ajs_1822 2-oxoglutarate dehydrogenase E1 component; PFAM: Transketolase-like, pyrimidine-binding domain; Dehydrogenase, E1 component.
 
 0.756
rplS
Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
   
 
 0.748
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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