Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AEB84477.1KEGG: ajs:Ajs_1637 XRE family transcriptional regulator; PFAM: Protein of unknown function DUF2083,transcriptional regulator; Helix-turn-helix type 3; Protein of unknown function DUF955; SMART: Helix-turn-helix type 3. (486 aa)    
Predicted Functional Partners:
AEB84475.1
TIGRFAM: 2-methylcitrate synthase/citrate synthase type I; KEGG: ajs:Ajs_1635 methylcitrate synthase; PFAM: Citrate synthase-like; Belongs to the citrate synthase family.
  
  
 0.666
AEB84476.1
KEGG: dia:Dtpsy_2078 thioesterase superfamily protein; manually curated; PFAM: Thioesterase superfamily.
 
   
 0.644
AEB84474.1
TIGRFAM: 2-methylisocitrate dehydratase AcnD, Fe/S-dependent; KEGG: dia:Dtpsy_2080 aconitate hydratase; PFAM: Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha; Aconitase A/isopropylmalate dehydratase small subunit, swivel.
  
  
 0.578
AEB85180.1
TIGRFAM: Isocitrate lyase; KEGG: dia:Dtpsy_1447 isocitrate lyase; PFAM: Isocitrate lyase/phosphorylmutase.
 
   
 0.549
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
 
   
 0.536
AEB84473.1
KEGG: dac:Daci_3586 AcnD-accessory protein PrpF; TIGRFAM: PrpF, AcnD-accessory; PFAM: PrpF protein.
     
 0.507
AEB84472.1
Methylisocitrate lyase; KEGG: dac:Daci_3579 PEP phosphonomutase; PFAM: Isocitrate lyase/phosphorylmutase.
 
   
 0.475
AEB83055.1
KEGG: dia:Dtpsy_0576 hypothetical protein.
  
     0.458
AEB85283.1
KEGG: pzu:PHZ_c2128 hypothetical protein.
   
 
 0.436
nrdR
Ribonucleotide reductase regulator NrdR-like protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
   
  
 0.409
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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