STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (331 aa)    
Predicted Functional Partners:
AEB82773.1
PFAM: Uncharacterised protein family UPF0093; KEGG: dia:Dtpsy_0263 hypothetical protein.
 
  
 0.938
AEB84713.1
KEGG: dia:Dtpsy_1711 radical SAM domain protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB.
  
 
 0.920
ctaB
Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
   
 
 0.915
ctaB-2
Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
   
 
 0.915
AEB83515.1
Bacterioferritin; Iron-storage protein.
     
 0.911
AEB84043.1
Bacterioferritin; Iron-storage protein.
     
 0.911
hemH-2
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
  
  
 
0.901
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.865
AEB84604.1
PFAM: Amine oxidase; KEGG: xal:XALc_2703 protoporphyrinogen oxidase protein.
  
  
 0.785
AEB85833.1
PFAM: Uroporphyrinogen decarboxylase (URO-D); KEGG: reu:Reut_B5441 uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family.
  
  
 0.737
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
Server load: medium (58%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.