Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEB84522.1Protein of unknown function UPF0125; PFAM: Uncharacterised protein family UPF0125; KEGG: ajs:Ajs_2550 hypothetical protein; Belongs to the UPF0125 (RnfH) family. (108 aa)    
Predicted Functional Partners:
AEB84521.1
Cyclase/dehydrase; PFAM: Streptomyces cyclase/dehydrase; KEGG: dia:Dtpsy_1257 cyclase/dehydrase.
  
  
 0.900
smpB
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
  
    0.662
AEB85745.1
Sporulation domain-containing protein; PFAM: Sporulation-related domain; KEGG: dia:Dtpsy_2228 sporulation domain protein.
  
    0.501
AEB84827.1
Electron transport complex, RnfABCDGE type, B subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
 
   
 0.431
recO
DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
  
     0.418
rlmD
23S rRNA (uracil-5-)-methyltransferase rumA; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
  
    0.413
AEB84519.1
KEGG: dia:Dtpsy_1255 secreted repeat of unknown function.
       0.406
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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