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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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[Homology]
Score
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (328 aa)    
Predicted Functional Partners:
AEB84578.1
KEGG: dia:Dtpsy_2288 type II citrate synthase; TIGRFAM: Citrate synthase, type II; PFAM: Citrate synthase-like; Belongs to the citrate synthase family.
  
 0.995
AEB86082.1
Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.995
AEB84475.1
TIGRFAM: 2-methylcitrate synthase/citrate synthase type I; KEGG: ajs:Ajs_1635 methylcitrate synthase; PFAM: Citrate synthase-like; Belongs to the citrate synthase family.
  
 0.994
fumC
Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.988
AEB83739.1
Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); PFAM: Phosphate acetyl/butaryl transferase; Malic enzyme, NAD-binding; Malic enzyme, N-terminal; KEGG: ajs:Ajs_1112 malic enzyme; SMART: Malic enzyme, NAD-binding.
  
 0.981
AEB87004.1
KEGG: dia:Dtpsy_3465 malic enzyme; PFAM: Phosphate acetyl/butaryl transferase; Malic enzyme, NAD-binding; Malic enzyme, N-terminal; SMART: Malic enzyme, NAD-binding.
  
 0.981
AEB85284.1
TIGRFAM: Isocitrate dehydrogenase NADP-dependent, prokaryotic; KEGG: aav:Aave_2572 isocitrate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase.
  
 0.980
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
   
 0.956
AEB85554.1
PFAM: Citrate synthase-like; KEGG: rme:Rmet_4144 citrate synthase.
  
 0.947
pckG
Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
 
  
 0.941
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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