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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobBSilent information regulator protein Sir2; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class II subfamily. (282 aa)    
Predicted Functional Partners:
AEB84689.1
KEGG: ajs:Ajs_1838 exonuclease I; PFAM: Exonuclease C-terminal; Exonuclease, RNase T/DNA polymerase III.
       0.782
AEB86843.1
KEGG: dia:Dtpsy_3340 nuclear protein SET; PFAM: SET domain; SMART: SET domain; Post-SET domain.
  
 
 0.651
AEB83192.1
Cytidyltransferase-related domain protein; KEGG: ajs:Ajs_0701 cytidyltransferase-like protein; TIGRFAM: Cytidyltransferase-related; PFAM: NUDIX hydrolase domain; Cytidylyltransferase.
  
  
 0.627
AEB85650.1
SMART: DEAD-like helicase, N-terminal; KEGG: ajs:Ajs_1578 helicase domain-containing protein.
   
    0.618
AEB84915.1
PFAM: Histone deacetylase superfamily; KEGG: ajs:Ajs_2813 histone deacetylase superfamily protein.
   
 
 0.616
AEB84688.1
KEGG: ajs:Ajs_1837 lytic murein transglycosylase; TIGRFAM: Lytic murein transglycosylase; PFAM: Peptidoglycan binding-like.
       0.576
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
   
 
 0.567
AEB82502.1
AraC protein arabinose-binding/dimerization; KEGG: dia:Dtpsy_0054 transcriptional regulator, AraC family; PFAM: HTH transcriptional regulator, AraC, arabinose-binding/dimerisation; SMART: Helix-turn-helix, AraC type, DNA binding domain.
  
  
 0.554
AEB82693.1
Cupin 2 conserved barrel domain protein; KEGG: dia:Dtpsy_0215 transcriptional regulator, AraC family; PFAM: Cupin 2, conserved barrel; SMART: Helix-turn-helix, AraC type, DNA binding domain.
  
  
 0.554
AEB83715.1
PFAM: Cytochrome P450; KEGG: ajs:Ajs_3226 cytochrome P450.
   
 0.552
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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