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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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gene co-occurrence
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cobBSilent information regulator protein Sir2; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class II subfamily. (282 aa)    
Predicted Functional Partners:
AEB84915.1
PFAM: Histone deacetylase superfamily; KEGG: ajs:Ajs_2813 histone deacetylase superfamily protein.
    
 0.817
AEB84689.1
KEGG: ajs:Ajs_1838 exonuclease I; PFAM: Exonuclease C-terminal; Exonuclease, RNase T/DNA polymerase III.
       0.779
AEB82551.1
TIGRFAM: DNA helicase, ATP-dependent, RecQ type, bacterial; DNA helicase, ATP-dependent, RecQ type; PFAM: RQC domain; Helicase, C-terminal; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase/RNase D C-terminal, HRDC domain; KEGG: dia:Dtpsy_0103 ATP-dependent DNA helicase RecQ; SMART: RQC domain; Helicase, C-terminal; DEAD-like helicase, N-terminal; Helicase/RNase D C-terminal, HRDC domain.
  
 
 0.772
AEB85648.1
KEGG: dia:Dtpsy_2175 hypothetical protein.
   
   0.755
AEB85649.1
KEGG: dia:Dtpsy_2176 hypothetical protein.
   
   0.755
AEB86843.1
KEGG: dia:Dtpsy_3340 nuclear protein SET; PFAM: SET domain; SMART: SET domain; Post-SET domain.
  
 
 0.745
AEB85650.1
SMART: DEAD-like helicase, N-terminal; KEGG: ajs:Ajs_1578 helicase domain-containing protein.
   
    0.619
AEB83192.1
Cytidyltransferase-related domain protein; KEGG: ajs:Ajs_0701 cytidyltransferase-like protein; TIGRFAM: Cytidyltransferase-related; PFAM: NUDIX hydrolase domain; Cytidylyltransferase.
  
  
 0.618
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.573
AEB82502.1
AraC protein arabinose-binding/dimerization; KEGG: dia:Dtpsy_0054 transcriptional regulator, AraC family; PFAM: HTH transcriptional regulator, AraC, arabinose-binding/dimerisation; SMART: Helix-turn-helix, AraC type, DNA binding domain.
  
    0.566
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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