Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEB84778.1TIGRFAM: PAS; PFAM: ATPase-like, ATP-binding domain; PAS fold; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; KEGG: dia:Dtpsy_1656 PAS/PAC sensor signal transduction histidine kinase; SMART: ATPase-like, ATP-binding domain; PAS; PAC motif; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain. (850 aa)    
Predicted Functional Partners:
AEB84777.1
KEGG: ctt:CtCNB1_2245 two component transcriptional regulator, LuxR; PFAM: Signal transduction response regulator, receiver domain; Transcription regulator LuxR, C-terminal; SMART: Signal transduction response regulator, receiver domain; Transcription regulator LuxR, C-terminal.
 
 
 0.963
AEB84741.1
PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold; Signal transduction response regulator, receiver domain; KEGG: dia:Dtpsy_1737 signal transduction histidine kinase, nitrogen specific, NtrB; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS; Signal transduction response regulator, receiver domain.
 
 
0.887
AEB82558.1
Sigma54 specific transcriptional regulator, Fis family; KEGG: dia:Dtpsy_0110 anaerobic nitric oxide reductase transcription regulator; PFAM: RNA polymerase sigma factor 54, interaction; Helix-turn-helix, Fis-type; SMART: ATPase, AAA+ type, core.
   
 
 0.829
AEB86747.1
KEGG: dac:Daci_2922 PAS/PAC sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold-4; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain.
  
 
 0.805
AEB86209.1
KEGG: dia:Dtpsy_2897 CheA signal transduction histidine kinase; PFAM: Signal transduction response regulator, receiver domain; ATPase-like, ATP-binding domain; Signal transduction histidine kinase, phosphotransfer (Hpt) domain; Signal transduction histidine kinase, subgroup, homodimeric; CheW-like protein; SMART: Signal transduction response regulator, receiver domain; ATPase-like, ATP-binding domain; Signal transduction histidine kinase, phosphotransfer (Hpt) domain; CheW-like protein.
  
 
 0.802
AEB86882.1
Two component transcriptional regulator, LuxR family; KEGG: ajs:Ajs_4015 response regulator receiver protein; PFAM: Transcription regulator LuxR, C-terminal; Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; Transcription regulator LuxR, C-terminal.
 
 
 0.781
AEB85617.1
KEGG: dia:Dtpsy_1366 phasin family protein; TIGRFAM: Phasin, subfamily 1; PFAM: Phasin.
  
     0.761
AEB86856.1
KEGG: dia:Dtpsy_3348 histidine kinase; PFAM: Two-component sensor kinase N-terminal; HAMP linker domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; ATPase-like, ATP-binding domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain.
 
 
 
 0.717
folD
Methylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
  
    0.706
AEB83329.1
KEGG: dia:Dtpsy_0798 hypothetical protein.
  
     0.672
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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