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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dapESuccinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (392 aa)    
Predicted Functional Partners:
AEB84826.1
TIGRFAM: Succinyldiaminopimelate transaminase, beta/gammaproteobacteria; KEGG: dia:Dtpsy_1889 succinyldiaminopimelate transaminase; PFAM: Aminotransferase, class I/classII.
 
  
 0.971
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
    
 0.933
argD
TIGRFAM: Acetylornithine/succinylornithine aminotransferase; KEGG: dia:Dtpsy_2429 acetylornithine aminotransferase; PFAM: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
  
 
 0.925
AEB84822.1
TIGRFAM: Ribosomal protein L3-specific, glutamine-N5-methyltransferase; Modification methylase HemK; KEGG: ajs:Ajs_2070 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; PFAM: Methyltransferase small; Belongs to the protein N5-glutamine methyltransferase family.
 
  
 0.911
dapD
KEGG: dia:Dtpsy_1890 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; TIGRFAM: 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family.
 
  
 0.836
AEB84821.1
PFAM: HTH transcriptional regulator, LysR; LysR, substrate-binding; KEGG: dac:Daci_3612 LysR family transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
   
 
 0.797
AEB84824.1
Twitching motility protein; TIGRFAM: Pilus retraction protein PilT; PFAM: Type II secretion system protein E; KEGG: dia:Dtpsy_1891 twitching motility protein; SMART: ATPase, AAA+ type, core.
       0.766
dnaQ
DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.
 
   
 0.587
rppH
NUDIX hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.
 
    0.578
AEB86517.1
KEGG: dia:Dtpsy_3080 flagellar motor switch protein FliG; TIGRFAM: Flagellar motor switch protein FliG; PFAM: Flagellar motor switch protein FliG, C-terminal.
   
   0.576
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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