Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEB84898.1KEGG: bpt:Bpet1117 metallo-beta-lactamase family protein; PFAM: Beta-lactamase-like; SMART: Beta-lactamase-like. (355 aa)    
Predicted Functional Partners:
AEB84319.1
KEGG: bxe:Bxe_C1205 putative superoxide dismutase; PFAM: Manganese/iron superoxide dismutase, C-terminal; SMART: Rhodanese-like.
 
 
 0.490
AEB84899.1
TIGRFAM: Glycine cleavage system T protein; KEGG: xtr:100488488 hypothetical protein LOC100488488; PFAM: Glycine cleavage T-protein, N-terminal; Glycine cleavage T-protein, C-terminal barrel.
  
  
 0.463
gcvP
Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
  
  
 0.439
AEB85533.1
PFAM: Ankyrin repeat; KEGG: dia:Dtpsy_1983 ankyrin.
   
 
 0.437
AEB86495.1
KEGG: dia:Dtpsy_3058 transcriptional regulator, MerR family; PFAM: Transcription regulator MerR, DNA binding; HTH transcriptional regulator, MerR; SMART: HTH transcriptional regulator, MerR.
 
   
 0.432
AEB85726.1
Rhodanese-like protein; KEGG: dia:Dtpsy_2204 transcriptional regulator, ArsR family; PFAM: Rhodanese-like; HTH transcriptional regulator, ArsR; SMART: HTH transcriptional regulator, ArsR; Rhodanese-like.
  
 
 0.406
ihfA
Integration host factor, alpha subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.
  
    0.402
AEB86949.1
KEGG: met:M446_5737 thioesterase superfamily protein; TIGRFAM: Phenylacetic acid degradation-related protein; PFAM: Thioesterase superfamily.
 
    0.401
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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