close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tsaDMetalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (347 aa)    
Predicted Functional Partners:
AEB86791.1
Universal protein YeaZ; KEGG: ajs:Ajs_3940 peptidase M22, glycoprotease; TIGRFAM: Conserved hypothetical protein CHP03725, YeaZ; PFAM: Peptidase M22, glycoprotease.
  
 
 0.945
AEB86357.1
Manually curated; TIGRFAM: Uncharacterised protein family UPF0079, ATPase bacteria; KEGG: dia:Dtpsy_0899 protein of unknown function UPF0079; PFAM: Uncharacterised protein family UPF0079, ATPase bacteria.
 
 
 0.909
rsmA
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
 
  
 0.764
pheS
KEGG: dia:Dtpsy_1452 phenylalanyl-tRNA synthetase subunit alpha; TIGRFAM: Phenylalanyl-tRNA synthetase, class IIc, alpha subunit; PFAM: Phenylalanyl-tRNA synthetase; Phenylalanyl-tRNA synthetase, class II, N-terminal; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
 
   
 0.728
AEB84937.1
KEGG: dia:Dtpsy_2323 putative signal transduction protein with CBS domains; PFAM: Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core.
       0.720
AEB84933.1
Phosphonate-transporting ATPase; PFAM: ABC transporter-like; KEGG: dia:Dtpsy_2313 ABC transporter related; SMART: ATPase, AAA+ type, core.
 
    0.680
lolD
Lipoprotein releasing system, ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
 
    0.666
AEB83503.1
KEGG: dia:Dtpsy_2764 SUA5/YciO/YrdC/YwlC family protein; TIGRFAM: Sua5/YciO/YrdC/YwlC; PFAM: Sua5/YciO/YrdC, N-terminal; Belongs to the SUA5 family.
  
 
 0.653
AEB86786.1
Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.
  
 
 0.653
pheT
TIGRFAM: Phenylalanyl-tRNA synthetase, class IIc, beta subunit, bacterial; KEGG: ajs:Ajs_2395 phenylalanyl-tRNA synthetase subunit beta; HAMAP: Phenylalanyl-tRNA synthetase, class IIc, beta subunit, bacterial; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
 
  
 0.650
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
Server load: low (22%) [HD]