Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEB84937.1KEGG: dia:Dtpsy_2323 putative signal transduction protein with CBS domains; PFAM: Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core. (145 aa)    
Predicted Functional Partners:
tsaD
Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
       0.719
AEB84938.1
KEGG: dia:Dtpsy_2324 calcium-binding EF-hand-containing protein.
       0.550
AEB83225.1
KEGG: ajs:Ajs_0741 glutamate synthase (NADH) large subunit; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal.
     
 0.501
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.488
AEB84934.1
KEGG: dia:Dtpsy_2314 efflux transporter, RND family, MFP subunit; TIGRFAM: Secretion protein HlyD; PFAM: Secretion protein HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
     
 0.486
AEB84935.1
KEGG: dia:Dtpsy_2315 RND efflux system, outer membrane lipoprotein, NodT family; TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT; PFAM: Outer membrane efflux protein.
     
 0.486
AEB84932.1
PFAM: Domain of unknown function DUF214, ABC transporter permease; KEGG: dia:Dtpsy_2312 protein of unknown function DUF214.
       0.465
AEB84933.1
Phosphonate-transporting ATPase; PFAM: ABC transporter-like; KEGG: dia:Dtpsy_2313 ABC transporter related; SMART: ATPase, AAA+ type, core.
       0.465
AEB84052.1
Phosphotransferase ydiA; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
  
  
 0.456
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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