close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB85019.1Two component transcriptional regulator PhoB, winged helix family; TIGRFAM: Signal transduction response regulator, phosphate regulon transcriptional regulatory protein PhoB; PFAM: Signal transduction response regulator, C-terminal; Signal transduction response regulator, receiver domain; KEGG: ajs:Ajs_2367 two component transcriptional regulator; SMART: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal. (233 aa)    
Predicted Functional Partners:
AEB85018.1
TIGRFAM: Signal transduction histidine kinase, phosphate regulon sensor PhoR; PFAM: ATPase-like, ATP-binding domain; PAS fold; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; KEGG: dia:Dtpsy_1492 PAS/PAC sensor signal transduction histidine kinase; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS.
 0.993
AEB85020.1
Phosphate uptake regulator, PhoU; Plays a role in the regulation of phosphate uptake.
 
  
 0.888
pstB
Phosphate ABC transporter, ATPase subunit; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
 
   
 0.868
AEB86397.1
TIGRFAM: PAS; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold-4; KEGG: dac:Daci_0735 PAS/PAC sensor signal transduction histidine kinase; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS.
 
 
 0.863
AEB83376.1
Manually curated; PFAM: Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; ATPase-like, ATP-binding domain; KEGG: dac:Daci_2713 histidine kinase; SMART: Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; ATPase-like, ATP-binding domain.
 
 
 0.857
AEB84157.1
TIGRFAM: Signal transduction histidine kinase, heavy metal sensor; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; KEGG: gbm:Gbem_2673 HAMP domain-containing sensor histidine kinase; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain.
 
 0.857
AEB82690.1
KEGG: dia:Dtpsy_0212 histidine kinase; PFAM: ATPase-like, ATP-binding domain; HAMP linker domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; HAMP linker domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain.
 
 0.837
AEB86401.1
TIGRFAM: PAS; PFAM: ATPase-like, ATP-binding domain; PAS fold-4; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; KEGG: dac:Daci_0735 PAS/PAC sensor signal transduction histidine kinase; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS.
 
 
 0.824
AEB86221.1
KEGG: aav:Aave_3963 integral membrane sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain.
 
 
 0.819
AEB84848.1
Integral membrane sensor signal transduction histidine kinase; KEGG: pol:Bpro_1451 histidine kinase; PFAM: Two-component sensor kinase N-terminal; ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain.
 
 
 0.812
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.