STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB85127.1PFAM: DNA methylase, adenine-specific; KEGG: hch:HCH_07036 type I restriction-modification system methyltransferase subunit. (995 aa)    
Predicted Functional Partners:
AEB84425.1
KEGG: mca:MCA0277 hypothetical protein.
 
 
 0.959
AEB84424.1
KEGG: xfm:Xfasm12_2267 type I restriction-modification system endonuclease; PFAM: Restriction endonuclease, type I, EcoRI, R subunit/Type III, Res subunit, N-terminal; Restriction endonuclease, type I, R subunit/Type III, Res subunit; SMART: DEAD-like helicase, N-terminal.
 
  
 0.826
AEB85128.1
KEGG: hch:HCH_07035 hypothetical protein.
       0.756
AEB84173.1
PFAM: DNA methylase N-4/N-6; KEGG: bpm:BURPS1710b_3656 adenine specific DNA methylase Mod.
 
   
 0.563
AEB84421.1
PFAM: Protein of unknown function DUF511; KEGG: dno:DNO_0218 hypothetical protein.
 
   0.544
uvrB
Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
   
 
 0.445
AEB85129.1
KEGG: seh:SeHA_C1592 helicase C2; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; SMART: DEAD-like helicase, N-terminal; Helicase, ATP-dependent, c2 type.
       0.407
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.