Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEB85216.1PFAM: Isochorismatase-like; KEGG: dia:Dtpsy_1824 isochorismatase hydrolase. (202 aa)    
Predicted Functional Partners:
gpsA
Manually curated; HAMAP: Glycerol-3-phosphate dehydrogenase, NAD-dependent; KEGG: xtr:100490244 glycerol-3-phosphate dehydrogenase [NAD(P)+]-like; PFAM: Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal; Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
  
   0.792
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 
 0.665
AEB85215.1
TIGRFAM: Propionate--CoA ligase; KEGG: dia:Dtpsy_1825 propionyl-CoA synthetase; PFAM: AMP-dependent synthetase/ligase.
       0.629
AEB85217.1
KEGG: dia:Dtpsy_1823 glucose sorbosone dehydrogenase.
       0.626
pncB
Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.
  
  
 0.495
AEB84046.1
Catalase; KEGG: gpb:HDN1F_12050 catalase; PFAM: Catalase-related subgroup; Catalase-related immune responsive; Belongs to the catalase family.
  
 
 0.488
AEB83598.1
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
   
 
 0.479
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.465
rpsL
Ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
  
  
 0.445
AEB84044.1
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
  
  
 0.436
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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