Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEB85262.1Transcriptional regulator, RpiR family; PFAM: Sugar isomerase (SIS); Helix-turn-helix protein RpiR; KEGG: dac:Daci_0986 RpiR family transcriptional regulator. (290 aa)    
Predicted Functional Partners:
AEB85261.1
5-dehydro-2-deoxygluconokinase; KEGG: dac:Daci_0985 ribokinase-like domain-containing protein; PFAM: Protein of unknown function DUF2090; Carbohydrate/purine kinase.
 
   
 0.939
AEB85260.1
PFAM: KduI/IolB isomerase; KEGG: rsc:RCFBP_20182 myo-inositol catabolism protein, protein IolB.
 
   
 0.901
AEB85263.1
DNA repair protein and transcriptional regulator, AraC family; KEGG: ajs:Ajs_2020 DNA-O6-methylguanine--protein-cysteine S-methyltransferase.
       0.588
AEB85264.1
methylated-DNA/protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
       0.460
AEB85265.1
PFAM: Drug/metabolite transporter; KEGG: dia:Dtpsy_1827 protein of unknown function DUF6 transmembrane.
       0.460
AEB86652.1
PFAM: Periplasmic binding protein/LacI transcriptional regulator; KEGG: azc:AZC_1419 ABC transporter sugar-binding protein.
 
  
 0.446
AEB83187.1
Transcriptional regulator, RpiR family; PFAM: Helix-turn-helix protein RpiR; Sugar isomerase (SIS); KEGG: ajs:Ajs_0694 RpiR family transcriptional regulator.
 
   
 0.441
AEB87041.1
Beta-aspartyl-peptidase; KEGG: aav:Aave_1656 asparaginase; PFAM: Peptidase T2, asparaginase 2.
  
    0.416
AEB85302.1
ABC-type transporter, integral membrane subunit; PFAM: Cobalt transport protein; KEGG: ajs:Ajs_2320 cobalt transport protein.
  
    0.402
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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