STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB85264.1methylated-DNA/protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (175 aa)    
Predicted Functional Partners:
AEB85263.1
DNA repair protein and transcriptional regulator, AraC family; KEGG: ajs:Ajs_2020 DNA-O6-methylguanine--protein-cysteine S-methyltransferase.
  
 0.945
AEB84679.1
DNA-3-methyladenine glycosylase II; SMART: HhH-GPD domain; manually curated; KEGG: dia:Dtpsy_2090 HhH-GPD family protein; PFAM: HhH-GPD domain.
 
  
 0.838
AEB85265.1
PFAM: Drug/metabolite transporter; KEGG: dia:Dtpsy_1827 protein of unknown function DUF6 transmembrane.
       0.837
AEB82910.1
KEGG: ajs:Ajs_0457 DNA-3-methyladenine glycosylase I; PFAM: Methyladenine glycosylase.
   
 0.755
AEB86067.1
KEGG: dia:Dtpsy_2749 hypothetical protein.
 
  
 0.680
AEB85262.1
Transcriptional regulator, RpiR family; PFAM: Sugar isomerase (SIS); Helix-turn-helix protein RpiR; KEGG: dac:Daci_0986 RpiR family transcriptional regulator.
     
 0.468
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 
 0.454
AEB83362.1
A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.
 
   
 0.442
AEB86190.1
UspA domain-containing protein; PFAM: UspA; Haemerythrin/HHE cation-binding motif; KEGG: reu:Reut_B3843 hypothetical protein.
  
    0.426
AEB85261.1
5-dehydro-2-deoxygluconokinase; KEGG: dac:Daci_0985 ribokinase-like domain-containing protein; PFAM: Protein of unknown function DUF2090; Carbohydrate/purine kinase.
     
 0.402
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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