Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
AEB85286.1TIGRFAM: Isocitrate dehydrogenase NADP-dependent, monomeric type; KEGG: ajs:Ajs_2300 isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate dehydrogenase NADP-dependent, monomeric type; Belongs to the monomeric-type IDH family. (745 aa)    
Predicted Functional Partners:
AEB84588.1
KEGG: ajs:Ajs_2787 bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; TIGRFAM: Aconitase B, bacterial; PFAM: Aconitase B, N-terminal, bacterial; Aconitase B, HEAT-like, bacterial; Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha; Belongs to the aconitase/IPM isomerase family.
 
 
 0.953
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
  
 0.939
AEB85284.1
TIGRFAM: Isocitrate dehydrogenase NADP-dependent, prokaryotic; KEGG: aav:Aave_2572 isocitrate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase.
    
 0.927
AEB85373.1
2-oxoglutarate dehydrogenase, E1 subunit; SMART: Transketolase-like, pyrimidine-binding domain; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 component; KEGG: ajs:Ajs_1822 2-oxoglutarate dehydrogenase E1 component; PFAM: Transketolase-like, pyrimidine-binding domain; Dehydrogenase, E1 component.
   
 
 0.924
AEB83383.1
Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
  
 
 0.921
AEB83778.1
Aconitate hydratase 1; TIGRFAM: Aconitase/iron regulatory protein 2; KEGG: ajs:Ajs_1145 aconitate hydratase; PFAM: Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha; Aconitase A/isopropylmalate dehydratase small subunit, swivel.
  
 
 0.921
AEB86937.1
CitB domain protein; TIGRFAM: Citrate utilization protein B; KEGG: ajs:Ajs_4071 CitB domain-containing protein.
  
  
 0.902
AEB83225.1
KEGG: ajs:Ajs_0741 glutamate synthase (NADH) large subunit; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal.
     
 0.879
AEB86890.1
TIGRFAM: Adenylosuccinate lyase; KEGG: dia:Dtpsy_3376 adenylosuccinate lyase; PFAM: Lyase 1, N-terminal; Adenylosuccinate lyase C-terminal/plant; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
   
 0.845
AEB82628.1
PFAM: Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal; Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain; KEGG: dia:Dtpsy_0153 Glu/Leu/Phe/Val dehydrogenase; SMART: Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 
 0.841
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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