STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB85324.1PFAM: Bacterial bifunctional deaminase-reductase, C-terminal; KEGG: mxa:MXAN_6138 riboflavin biosynthesis protein RibD domain-containing protein. (186 aa)    
Predicted Functional Partners:
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
  
 0.809
AEB85325.1
Protein of unknown function DUF2309; PFAM: Uncharacterised protein family UPF0753; KEGG: mei:Msip34_2093 hypothetical protein; Belongs to the UPF0753 family.
       0.598
hemH-2
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
     
 0.572
AEB85326.1
NADH/Ubiquinone/plastoquinone (complex I); PFAM: NADH:ubiquinone/plastoquinone oxidoreductase; KEGG: mei:Msip34_2092 NADH dehydrogenase subunit L.
     
 0.549
AEB84354.1
Chorismate mutase; TIGRFAM: Gamma/beta/epsilon proteobacterial P-protein, chorismate mutase domain; PFAM: Prephenate dehydratase; Chorismate mutase, type II; Amino acid-binding ACT; KEGG: dia:Dtpsy_1394 chorismate mutase; SMART: Chorismate mutase.
     
 0.516
AEB86223.1
KEGG: app:CAP2UW1_1324 oxidoreductase FAD-binding domain protein; PFAM: Oxidoreductase, FAD-binding domain; Ferredoxin; Cytochrome b/b6, N-terminal; Oxidoreductase FAD/NAD(P)-binding.
     
 0.487
AEB85202.1
KEGG: gur:Gura_0848 3-demethylubiquinone-9 3-methyltransferase.
 
    0.465
AEB83598.1
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.447
AEB82685.1
PFAM: Activator of Hsp90 ATPase homologue 1-like; KEGG: oca:OCAR_5014 activator of HSP90 ATPase 1 family protein.
 
     0.432
AEB83420.1
TIGRFAM: Para-aminobenzoate synthase, component I; KEGG: ajs:Ajs_3496 para-aminobenzoate synthase, subunit I; PFAM: Chorismate binding, C-terminal; Aminotransferase, class IV.
  
  
 0.418
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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