Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEB85448.1TIGRFAM: Phosphomethylpyrimidine kinase type-2; KEGG: ajs:Ajs_1787 phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. (282 aa)    
Predicted Functional Partners:
AEB85452.1
KEGG: dia:Dtpsy_1939 thiamine-phosphate pyrophosphorylase; PFAM: Thiamine monophosphate synthase.
 
 0.999
thiC
Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
 
 
 0.989
thiG
Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
  
 0.964
AEB86203.1
PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: dia:Dtpsy_2903 phosphomethylpyrimidine kinase type-1.
  
  
 
0.928
AEB85450.1
KEGG: dia:Dtpsy_1937 thiamine biosynthesis protein ThiS; TIGRFAM: ThiS, thiamine-biosynthesis; PFAM: ThiamineS.
  
  
 0.901
AEB85449.1
Glycine oxidase ThiO; KEGG: dia:Dtpsy_1936 FAD dependent oxidoreductase; TIGRFAM: Glycine oxidase ThiO; PFAM: FAD dependent oxidoreductase.
 
  
 0.740
AEB83403.1
PFAM: UBA/THIF-type NAD/FAD binding fold; MoeZ/MoeB; KEGG: ajs:Ajs_3507 UBA/ThiF-type NAD/FAD binding protein.
 
  
 0.701
AEB85629.1
PRTRC system ThiF family protein; KEGG: ajs:Ajs_1597 UBA/ThiF-type NAD/FAD binding protein; TIGRFAM: ParB-related, ThiF-related cassette, ThiF; PFAM: UBA/THIF-type NAD/FAD binding fold.
  
  
 0.596
AEB83765.1
KEGG: dia:Dtpsy_1053 DEAD/DEAH box helicase domain protein; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; Belongs to the DEAD box helicase family.
 
    0.584
rhlE
DEAD/DEAH box helicase domain protein; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA.
 
    0.562
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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