STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
thiGThiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (267 aa)    
Predicted Functional Partners:
AEB85452.1
KEGG: dia:Dtpsy_1939 thiamine-phosphate pyrophosphorylase; PFAM: Thiamine monophosphate synthase.
  
 0.998
AEB85449.1
Glycine oxidase ThiO; KEGG: dia:Dtpsy_1936 FAD dependent oxidoreductase; TIGRFAM: Glycine oxidase ThiO; PFAM: FAD dependent oxidoreductase.
 
 0.997
AEB85450.1
KEGG: dia:Dtpsy_1937 thiamine biosynthesis protein ThiS; TIGRFAM: ThiS, thiamine-biosynthesis; PFAM: ThiamineS.
 
 
 0.996
thiC
Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
 
  
 0.978
AEB85448.1
TIGRFAM: Phosphomethylpyrimidine kinase type-2; KEGG: ajs:Ajs_1787 phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1.
 
  
 0.964
dxs
Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
     
 0.928
AEB83403.1
PFAM: UBA/THIF-type NAD/FAD binding fold; MoeZ/MoeB; KEGG: ajs:Ajs_3507 UBA/ThiF-type NAD/FAD binding protein.
 
  
 0.911
AEB84968.1
D-amino-acid dehydrogenase; KEGG: bam:Bamb_3394 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase.
 
  
 0.875
AEB86203.1
PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: dia:Dtpsy_2903 phosphomethylpyrimidine kinase type-1.
 
  
 0.827
AEB83585.1
KEGG: dia:Dtpsy_2555 molybdopterin converting factor, subunit 1; TIGRFAM: Molybdopterin converting factor, subunit 1; PFAM: ThiamineS.
   
 
 0.823
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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