Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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AEB85480.1KEGG: dia:Dtpsy_1960 nitrogen regulatory protein P-II; PFAM: Nitrogen regulatory protein PII; SMART: Nitrogen regulatory protein PII; Belongs to the P(II) protein family. (112 aa)    
Predicted Functional Partners:
AEB82650.1
KEGG: ajs:Ajs_0164 ammonium transporter; TIGRFAM: Ammonium transporter; PFAM: Ammonium transporter.
 
 0.996
AEB83832.1
Manually curated; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; KEGG: dia:Dtpsy_1111 signal transduction histidine kinase, nitrogen specific, NtrB; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain.
  
 0.978
glnD
UTP-GlnB uridylyltransferase, GlnD; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
 
 
 0.977
AEB85732.1
KEGG: dia:Dtpsy_2211 nitrogen regulatory protein P-II; PFAM: Nitrogen regulatory protein PII; SMART: Nitrogen regulatory protein PII.
  
  
 
0.915
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
     
 0.791
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
  
 
 
 0.778
argA
Amino-acid N-acetyltransferase; KEGG: ajs:Ajs_2327 N-acetylglutamate synthase; TIGRFAM: Amino-acid N-acetyltransferase (ArgA); PFAM: Aspartate/glutamate/uridylate kinase; GCN5-related N-acetyltransferase (GNAT) domain; Belongs to the acetyltransferase family. ArgA subfamily.
   
 
 0.747
gph
Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
  
   
 0.723
AEB83830.1
TIGRFAM: Glutamine synthetase type I; KEGG: aav:Aave_1442 L-glutamine synthetase; PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp.
 
 
 0.682
flhC
Flagellar transcriptional activator FlhC; Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhC family.
      
 0.674
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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