close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB85534.1KEGG: ajs:Ajs_1720 TatD family hydrolase; TIGRFAM: Deoxyribonuclease, TatD Mg-dependent, prokaryote; PFAM: Deoxyribonuclease, TatD-related. (269 aa)    
Predicted Functional Partners:
mltG
Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.
    
 0.871
AEB85533.1
PFAM: Ankyrin repeat; KEGG: dia:Dtpsy_1983 ankyrin.
       0.821
AEB85536.1
KEGG: ajs:Ajs_1718 DNA-directed DNA polymerase.
 
  
 0.760
AEB85535.1
PFAM: Type IV pilus assembly PilZ; KEGG: dia:Dtpsy_1985 type IV pilus assembly PilZ.
  
    0.751
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
     
 0.697
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
 
 
 0.595
dnaX
DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
 
   
 0.537
AEB85539.1
Folate-binding protein YgfZ; KEGG: ajs:Ajs_1715 glycine cleavage T protein (aminomethyl transferase); TIGRFAM: Folate-binding, YgfZ; PFAM: Glycine cleavage T-protein, N-terminal; Glycine cleavage T-protein, C-terminal barrel; Belongs to the GcvT family.
       0.508
erpA
Iron-sulfur cluster assembly accessory protein; Required for insertion of 4Fe-4S clusters.
 
   0.457
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
 
  
 0.452
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.