Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEB85534.1KEGG: ajs:Ajs_1720 TatD family hydrolase; TIGRFAM: Deoxyribonuclease, TatD Mg-dependent, prokaryote; PFAM: Deoxyribonuclease, TatD-related. (269 aa)    
Predicted Functional Partners:
mltG
Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.
    
 0.873
AEB85533.1
PFAM: Ankyrin repeat; KEGG: dia:Dtpsy_1983 ankyrin.
       0.815
AEB85536.1
KEGG: ajs:Ajs_1718 DNA-directed DNA polymerase.
 
  
 0.765
AEB85535.1
PFAM: Type IV pilus assembly PilZ; KEGG: dia:Dtpsy_1985 type IV pilus assembly PilZ.
  
    0.747
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
     
 0.693
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
 
 0.560
dnaX
DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
 
   
 0.547
AEB85539.1
Folate-binding protein YgfZ; KEGG: ajs:Ajs_1715 glycine cleavage T protein (aminomethyl transferase); TIGRFAM: Folate-binding, YgfZ; PFAM: Glycine cleavage T-protein, N-terminal; Glycine cleavage T-protein, C-terminal barrel; Belongs to the GcvT family.
       0.543
tsaD
Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
  
   
 0.487
AEB85540.1
PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: dia:Dtpsy_2009 CMP/dCMP deaminase zinc-binding.
  
    0.459
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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