Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEB85629.1PRTRC system ThiF family protein; KEGG: ajs:Ajs_1597 UBA/ThiF-type NAD/FAD binding protein; TIGRFAM: ParB-related, ThiF-related cassette, ThiF; PFAM: UBA/THIF-type NAD/FAD binding fold. (281 aa)    
Predicted Functional Partners:
AEB85631.1
PRTRC system protein B; TIGRFAM: ParB-related, ThiF-related cassette, protein B; KEGG: ajs:Ajs_1595 hypothetical protein.
 
     0.914
AEB83590.1
PFAM: Molybdopterin biosynthesis MoaE; KEGG: ajs:Ajs_3199 molybdopterin synthase subunit MoaE.
  
 0.872
AEB85450.1
KEGG: dia:Dtpsy_1937 thiamine biosynthesis protein ThiS; TIGRFAM: ThiS, thiamine-biosynthesis; PFAM: ThiamineS.
  
 
 0.871
thiG
Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
  
  
 0.834
AEB85630.1
KEGG: ajs:Ajs_1596 hypothetical protein; TIGRFAM: ParB-related, ThiF-related cassette, protein A; PFAM: Domain of unknown function DUF2016.
  
 0.818
AEB85121.1
PRTRC system protein B; TIGRFAM: ParB-related, ThiF-related cassette, protein B; KEGG: ajs:Ajs_1595 hypothetical protein.
 
     0.790
AEB83585.1
KEGG: dia:Dtpsy_2555 molybdopterin converting factor, subunit 1; TIGRFAM: Molybdopterin converting factor, subunit 1; PFAM: ThiamineS.
  
 
 0.789
AEB85628.1
Hypothetical protein.
       0.777
thiC
Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
  
  
 0.723
AEB85452.1
KEGG: dia:Dtpsy_1939 thiamine-phosphate pyrophosphorylase; PFAM: Thiamine monophosphate synthase.
  
  
 0.665
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.