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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppnPProtein of unknown function DUF1255; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. (105 aa)    
Predicted Functional Partners:
AEB85078.1
KEGG: ajs:Ajs_2690 thymidine phosphorylase; PFAM: Pyrimidine nucleoside phosphorylase, C-terminal; Glycosyl transferase, family 3; TIGRFAM: Thymidine phosphorylase, type 2; HAMAP: Thymidine phosphorylase, type 2; SMART: Pyrimidine nucleoside phosphorylase, C-terminal.
     
 0.909
AEB85710.1
KEGG: ajs:Ajs_1507 thymidine phosphorylase; PFAM: Pyrimidine nucleoside phosphorylase, C-terminal; Glycosyl transferase, family 3; TIGRFAM: Thymidine phosphorylase, type 2; HAMAP: Thymidine phosphorylase, type 2; SMART: Pyrimidine nucleoside phosphorylase, C-terminal.
     
 0.909
AEB85883.1
Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.
    
 0.907
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
    
  0.902
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
     
 0.901
amn
AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.
     
  0.900
AEB83159.1
5'-nucleotidase; KEGG: vei:Veis_1630 5-nucleotidase; PFAM: 5-nucleotidase.
     
  0.900
surE
Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
  0.900
AEB86159.1
Adenosine kinase; KEGG: dia:Dtpsy_2945 PfkB domain protein; PFAM: Carbohydrate/purine kinase.
     
  0.900
AEB86212.1
KEGG: dia:Dtpsy_2894 phosphoribosyltransferase; PFAM: Phosphoribosyltransferase.
     
  0.900
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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