Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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[Homology]
Score
AEB85904.1PFAM: Heat shock protein Hsp20; KEGG: dia:Dtpsy_2459 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family. (142 aa)    
Predicted Functional Partners:
AEB84437.1
PFAM: Heat shock protein Hsp20; KEGG: rpf:Rpic12D_0629 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family.
  
  
 
0.916
AEB84436.1
KEGG: mfa:Mfla_1170 ATPase AAA-2; PFAM: ATPase, AAA-2; ATPase, AAA-type, core; Clp, N-terminal; Clp ATPase, C-terminal; SMART: ATPase, AAA+ type, core; Belongs to the ClpA/ClpB family.
 
 
 0.825
clpB
ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
 
 
 0.792
AEB85363.1
TIGRFAM: ATP-dependent Clp protease ATP-binding subunit ClpA; PFAM: ATPase, AAA-2; ATPase, AAA-type, core; Clp, N-terminal; Clp ATPase, C-terminal; KEGG: dia:Dtpsy_1896 ATP-dependent Clp protease, ATP-binding subunit ClpA; SMART: ATPase, AAA+ type, core; Belongs to the ClpA/ClpB family.
  
 
 0.759
AEB83830.1
TIGRFAM: Glutamine synthetase type I; KEGG: aav:Aave_1442 L-glutamine synthetase; PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp.
    
 
 0.706
htpG
Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity.
  
 
 0.657
hslV
ATP-dependent protease HslVU, peptidase subunit; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
  
  
 0.566
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
 
 0.562
AEB83089.1
KEGG: dia:Dtpsy_0618 heat shock protein DnaJ domain protein; PFAM: Heat shock protein DnaJ, N-terminal; Chaperone DnaJ, C-terminal; SMART: Heat shock protein DnaJ, N-terminal.
  
 
 0.551
AEB85905.1
PFAM: Domain of unknown function DUF214, ABC transporter permease; KEGG: dia:Dtpsy_2460 protein of unknown function DUF214.
       0.547
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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