Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEB85953.1KEGG: dia:Dtpsy_2668 carboxymethylenebutenolidase; PFAM: Dienelactone hydrolase. (294 aa)    
Predicted Functional Partners:
AEB82765.1
KEGG: dia:Dtpsy_0255 carboxymethylenebutenolidase; PFAM: Dienelactone hydrolase.
  
  
 
0.923
gyrA
DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
      
 0.635
AEB85952.1
PFAM: Zinc/iron permease; KEGG: dia:Dtpsy_2667 zinc/iron permease.
  
  
 0.627
AEB83467.1
KEGG: ajs:Ajs_3456 hypothetical protein.
  
  
 0.609
AEB85954.1
Enoyl-CoA hydratase/isomerase; PFAM: Crotonase, core; KEGG: bpt:Bpet4160 putative enoyl-CoA hydratase.
       0.548
AEB85955.1
KEGG: bpt:Bpet4161 acyl-CoA transferase/carnitine dehydratase; PFAM: CoA-transferase family III; Belongs to the CoA-transferase III family.
  
  
 0.527
AEB86223.1
KEGG: app:CAP2UW1_1324 oxidoreductase FAD-binding domain protein; PFAM: Oxidoreductase, FAD-binding domain; Ferredoxin; Cytochrome b/b6, N-terminal; Oxidoreductase FAD/NAD(P)-binding.
 
 
 0.488
AEB85956.1
KEGG: bpt:Bpet4162 putative secreted protein.
       0.455
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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