Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
AEB85967.1Diguanylate cyclase with extracellular sensor; TIGRFAM: Diguanylate cyclase, predicted; PFAM: Diguanylate cyclase, predicted; Extracellular solute-binding protein, family 3; KEGG: dba:Dbac_1471 diguanylate cyclase; SMART: Diguanylate cyclase, predicted; Extracellular solute-binding protein, family 3. (538 aa)    
Predicted Functional Partners:
AEB86400.1
KEGG: dac:Daci_0737 metal dependent phosphohydrolase; PFAM: Metal-dependent phosphohydrolase, HD subdomain; SMART: Metal-dependent phosphohydrolase, HD domain.
  
 0.873
AEB82555.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: Diguanylate cyclase, predicted; PAS; PFAM: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; PAS fold; PAS fold-4; KEGG: ajs:Ajs_0088 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); SMART: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; PAC motif; PAS.
 
 
0.769
AEB86480.1
TIGRFAM: Diguanylate cyclase, predicted; PFAM: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; KEGG: rfr:Rfer_2485 diguanylate cyclase/phosphodiesterase; SMART: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted.
 
 
0.769
AEB86773.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); TIGRFAM: Diguanylate cyclase, predicted; PAS; PFAM: Diguanylate cyclase, predicted; PAS fold; GAF; Diguanylate phosphodiesterase, EAL domain; KEGG: bxe:Bxe_C0015 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); SMART: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; PAS; PAC motif; GAF.
 
 
0.714
AEB82465.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); TIGRFAM: Diguanylate cyclase, predicted; PAS; PFAM: Diguanylate phosphodiesterase, EAL domain; PAS fold; Diguanylate cyclase, predicted; GAF; KEGG: dia:Dtpsy_0021 diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); SMART: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; PAS; PAC motif; GAF.
 
 
0.713
AEB86683.1
Metal dependent phosphohydrolase; TIGRFAM: Uncharacterised protein family HDIG; PFAM: Metal-dependent phosphohydrolase, HD subdomain; KEGG: dia:Dtpsy_0366 metal dependent phosphohydrolase; SMART: Metal-dependent phosphohydrolase, HD domain.
 
 0.655
AEB86702.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: Diguanylate cyclase, predicted; PAS; PFAM: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; PAS fold; HAMP linker domain; KEGG: slt:Slit_0879 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); SMART: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; PAS; HAMP linker domain; PAC motif.
 
 
0.645
AEB84800.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC and Chase sensor(s); TIGRFAM: Diguanylate cyclase, predicted; PAS; PFAM: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; CHASE; PAS fold; KEGG: dia:Dtpsy_1667 diguanylate cyclase/phosphodiesterase with PAS/PAC and CHASE sensor(s); SMART: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; PAS; PAC motif.
 
 
0.627
AEB84961.1
PFAM: Metal-dependent phosphohydrolase, HD subdomain; KEGG: ajs:Ajs_1963 metal dependent phosphohydrolase.
 
 
 0.621
AEB86477.1
Diguanylate cyclase with PAS/PAC sensor; TIGRFAM: Diguanylate cyclase, predicted; PAS; PFAM: Diguanylate cyclase, predicted; PAS fold-3; KEGG: dia:Dtpsy_3048 diguanylate cyclase with PAS/PAC sensor; SMART: Diguanylate cyclase, predicted.
 
 
0.621
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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