Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEB86054.1KEGG: aav:Aave_3461 Na/Pi-cotransporter II-related protein; TIGRFAM: Na/Pi co-transporter II-related; PFAM: Na/Pi-cotransporter; PhoU. (555 aa)    
Predicted Functional Partners:
cpdA
Metallophosphoesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.
 
     0.757
AEB86051.1
ABC-type transporter, integral membrane subunit; PFAM: Binding-protein-dependent transport systems inner membrane component; KEGG: vap:Vapar_1263 binding-protein-dependent transport systems inner membrane component.
       0.710
AEB86052.1
Polyamine-transporting ATPase; PFAM: ABC transporter-like; Transport-associated OB, type 2; KEGG: vap:Vapar_1262 ABC transporter related; SMART: ATPase, AAA+ type, core; Belongs to the ABC transporter superfamily.
       0.701
AEB86049.1
PFAM: Bacterial extracellular solute-binding, family 1; KEGG: vap:Vapar_1265 extracellular solute-binding protein family 1.
       0.662
AEB86050.1
ABC-type transporter, integral membrane subunit; PFAM: Binding-protein-dependent transport systems inner membrane component; KEGG: vap:Vapar_1264 binding-protein-dependent transport systems inner membrane component.
       0.638
AEB86048.1
KEGG: vap:Vapar_1266 transcriptional regulator, LacI family; PFAM: Periplasmic binding protein/LacI transcriptional regulator; HTH transcriptional regulator, LacI; SMART: HTH transcriptional regulator, LacI.
       0.526
lspA-2
Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
       0.477
AEB86863.1
Phosphonoacetate hydrolase; KEGG: reu:Reut_B5876 type I phosphodiesterase/nucleotide pyrophosphatase; TIGRFAM: Phosphonoacetate hydrolase; PFAM: Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase.
 
     0.460
ileS
Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
       0.408
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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