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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
fumCFumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (461 aa)    
Predicted Functional Partners:
AEB84581.1
TIGRFAM: Succinate dehydrogenase, flavoprotein subunit; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; KEGG: dia:Dtpsy_2285 succinate dehydrogenase, flavoprotein subunit; PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
 
 0.992
AEB86082.1
Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.985
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.972
AEB84580.1
TIGRFAM: Succinate dehydrogenase/fumarate reductase iron-sulphur protein; KEGG: dac:Daci_2424 succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: Ferredoxin.
  
 0.971
AEB83452.1
KEGG: dia:Dtpsy_2798 respiratory-chain NADH dehydrogenase domain 51 kDa subunit; PFAM: NADH:ubiquinone oxidoreductase, 51kDa subunit; NADH:ubiquinone oxidoreductase, 24kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; SMART: NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding.
  
 0.970
AEB83739.1
Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); PFAM: Phosphate acetyl/butaryl transferase; Malic enzyme, NAD-binding; Malic enzyme, N-terminal; KEGG: ajs:Ajs_1112 malic enzyme; SMART: Malic enzyme, NAD-binding.
  
 
 0.970
AEB87004.1
KEGG: dia:Dtpsy_3465 malic enzyme; PFAM: Phosphate acetyl/butaryl transferase; Malic enzyme, NAD-binding; Malic enzyme, N-terminal; SMART: Malic enzyme, NAD-binding.
  
 
 0.970
AEB84583.1
KEGG: dia:Dtpsy_2283 succinate dehydrogenase, cytochrome b556 subunit; TIGRFAM: Succinate dehydrogenase, cytochrome b556 subunit; PFAM: Succinate dehydrogenase/Fumarate reductase, transmembrane subunit.
  
 
 0.967
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
    
 0.931
AEB84582.1
KEGG: aav:Aave_2203 succinate dehydrogenase subunit D; TIGRFAM: Succinate dehydrogenase, hydrophobic membrane anchor; PFAM: Succinate dehydrogenase/Fumarate reductase, transmembrane subunit.
  
 
 0.927
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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