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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB86117.1Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (408 aa)    
Predicted Functional Partners:
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
 
  
 0.967
coaD
Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
 
  
 0.946
coaX
Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
 
 
 0.941
panC
Pantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
 
 
 0.899
AEB85502.1
KEGG: rso:RSp1232 aspartate aminotransferase A protein; PFAM: Aminotransferase, class I/classII.
  
  0.841
AEB85210.1
Cystathionine beta-lyase; KEGG: dia:Dtpsy_1601 Cys/Met metabolism pyridoxal-phosphate-dependent protein; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme.
  
 
  0.836
AEB85831.1
PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; KEGG: hch:HCH_06702 cysteine synthase.
    
 0.813
AEB85906.1
Cysteine synthase; KEGG: ajs:Ajs_3115 pyridoxal-5'-phosphate-dependent enzyme, beta subunit; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit.
    
 0.813
AEB86410.1
TIGRFAM: Cysteine synthase K/M; Cysteine synthase A; KEGG: dac:Daci_1442 cysteine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
 0.813
AEB86116.1
Hypothetical protein.
       0.773
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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