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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB86203.1PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: dia:Dtpsy_2903 phosphomethylpyrimidine kinase type-1. (300 aa)    
Predicted Functional Partners:
AEB85452.1
KEGG: dia:Dtpsy_1939 thiamine-phosphate pyrophosphorylase; PFAM: Thiamine monophosphate synthase.
 
 
 0.982
thiC
Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
  
 
 0.980
AEB85448.1
TIGRFAM: Phosphomethylpyrimidine kinase type-2; KEGG: ajs:Ajs_1787 phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1.
  
  
 
0.928
hemL
Glutamate-1-semialdehyde-2,1-aminomutase; TIGRFAM: Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase; KEGG: dia:Dtpsy_2904 glutamate-1-semialdehyde aminotransferase; PFAM: Aminotransferase class-III.
  
  
 0.861
thiG
Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
  
 0.827
AEB85450.1
KEGG: dia:Dtpsy_1937 thiamine biosynthesis protein ThiS; TIGRFAM: ThiS, thiamine-biosynthesis; PFAM: ThiamineS.
  
    0.771
AEB86204.1
KEGG: aav:Aave_0900 rubredoxin-type Fe(Cys)4 protein; manually curated; PFAM: Rubredoxin-type Fe(Cys)4 protein; Belongs to the rubredoxin family.
  
    0.614
AEB83403.1
PFAM: UBA/THIF-type NAD/FAD binding fold; MoeZ/MoeB; KEGG: ajs:Ajs_3507 UBA/ThiF-type NAD/FAD binding protein.
 
  
 0.599
AEB83598.1
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
  
 0.581
AEB86206.1
KEGG: dia:Dtpsy_2900 response regulator receiver protein; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain.
  
    0.538
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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